FBXW4 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human FBXW4 wild-type allele is located in the vicinity of 10q24 and is approximately 85 kb in length. This allele, which encodes F-box/WD repeat-containing protein 4, is involved in the mediation of both limb morphogenesis and protein catabolism. Mutations in the gene are associated with split-hand/foot malformation type 3.

**Synonyms:** - DAC - F-Box And WD Repeat Domain Containing 4 wt Allele - FBW4 - FBWD4 - SHFM3 - SHSF3