FMR1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human FMR1 wild-type allele is located in the vicinity of Xq27.3 and is approximately 39 kb in length. This allele, which encodes fragile X messenger ribonucleoprotein 1, may play a role in the mediation of mRNA transport. Amplification of a trinucleotide repeat (CGG) within the gene is associated with fragile X syndrome.

**Synonyms:** - FMRP - FMRP Translational Regulator 1 Gene - FRAXA - Fragile X Mental Retardation 1 Gene - Fragile X Messenger Ribonucleoprotein 1 wt Allele - MGC87458 - POF - POF1 - Premature Ovarian Failure 1 Gene - Synaptic Functional Regulator FMR1 Gene