UBE3A wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human UBE3A wild-type allele is located within 15q11-q13 and is approximately 102 kb in length. This allele, which encodes ubiquitin-protein ligase E3A, plays a role in protein turnover by targeting substrate proteins for degradation. Mutations in this gene are associated with Angelman syndrome.

**Synonyms:** - ANCR - AS - E6-AP - E6AP - EPVE6AP - FLJ26981 - HPVE6A - Ubiquitin Protein Ligase E3A (Human Papilloma Virus E6-Associated Protein, Angelman Syndrome) wt Allele