SIM1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human SIM1 wild-type allele is located within 6q16.3-q21 and is approximately 80 kb in length. This allele, which encodes single-minded homolog 1 protein, plays roles in regulation of transcription, neurogenesis, and may also play a role in regulation of feeding behavior. Mutations in this gene are associated with a Prader-Willi-like phenotype.

**Synonyms:** - Single-Minded Homolog 1 (Drosophila) wt Allele