HIRA wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human HIRA wild-type allele is located in the vicinity of 22q11.2 or 22q11.21 and is approximately 101 kb in length. This allele, which encodes protein HIRA, is involved in the modulation of chromatin structure. Haploinsufficiency of the gene may be a factor in DiGeorge syndrome.

**Synonyms:** - DGCR1 - DiGeorge Critical Region Gene 1 - DiGeorge Syndrome Critical Region Gene 1 - HIR - HIR (Histone Cell Cycle Regulation Defective) Homolog A (S. cerevisiae) Gene - HIR Histone Cell Cycle Regulation Defective Homolog A (S. cerevisiae) Gene - HIR, S. cerevisiae, Homolog of Gene - Histone Cell Cycle Regulation Defective, S. cerevisiae, Homolog of, A Gene - Histone Cell Cycle Regulator wt Allele - TUP-Like Enhancer of Split 1 Gene - TUP1 - TUPLE1