SIX3 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human SIX3 wild-type allele is located within 2p16-p21 and is approximately 4 kb in length. This allele, which encodes homeobox protein SIX3, plays a role in retinal development. Mutations in this gene are associated with holoprosencephaly 2.

**Synonyms:** - HPE2 - SIX Homeobox 3 wt Allele - Sine Oculis Homeobox, Drosophila, Homolog of, 3 Gene