IDS wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human IDS wild-type allele is located in the vicinity of Xq28 and is approximately 27 kb in length. This allele, which encodes iduronate 2-sulfatase protein, plays a role in the mediation of proteoglycan turnover. Mutations in the gene that result in enzymatic deficiency of the gene product are associated with Mucopolysaccharidosis Type II (Hunter Syndrome).

**Synonyms:** - Iduronate 2-Sulfatase (Hunter Syndrome) wt Allele - MPS2 - SIDS