KCNQ1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human KCNQ1 wild-type allele is located in the vicinity of 11p15.5 and is approximately 404 kb in length. This allele, which encodes potassium voltage-gated channel subfamily KQT member 1 protein, plays a role in the regulation of both cardiac repolarization and potassium transport. Mutations in the gene are associated with hereditary long QT syndrome, Romano-Ward syndrome, Jervell and Lange-Nielsen syndrome and familial atrial fibrillation.

**Synonyms:** - ATFB1 - ATFB3 - FLJ26167 - JLNS1 - Jervell and Lange-Nielsen Syndrome 1 Gene - KCNA8 - KCNA9 - KVLQT1 - Kv1.9 - Kv7.1 - LQT - LQT1 - Potassium Channel, Voltage-Gated, KQT-Like Subfamily, Member 1 Gene - Potassium Channel, Voltage-Gated, Shaker-Related Subfamily, Member 9 Gene - Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 wt Allele - RWS - SQT2 - WRS