MAPT wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human MAPT wild-type allele is located in the vicinity of 17q21.1 and is approximately 134 kb in length. This allele, which encodes microtubule-associated protein tau, may play a role in the development and maintenance of neuronal polarity. Mutations in the gene are associated with a large number of neurodegenerative diseases.

**Synonyms:** - DDPAC - FLJ31424 - FTDP-17 - MAPTL - MGC138549 - MSTD - MTBT1 - MTBT2 - Microtubule-Associated Protein Tau wt Allele - PPND - TAU