NSD1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human NSD1 wild-type allele is located within 5q35.2-q35.3 and is approximately 162 kb in length. This allele, which encodes histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific protein, plays a role in the modulation of histone methylation. Mutations and translocations of the gene are involved in several diseases.

**Synonyms:** - ARA267 - DKFZp666C163 - FLJ10684 - FLJ22263 - FLJ44628 - KMT3B - Nuclear Receptor Binding SET Domain Protein 1 wt Allele - Nuclear Receptor-Binding Su-Var, Enhancer of Zeste, and Trithorax Domain Protein 1 Gene - SOTOS - SOTOS1 - STO - Sotos Syndrome Gene