Acute Myeloid Leukemia, Myelodysplasia-Related

**Semantic type:** Neoplastic Process

**Definition:** An acute myeloid leukemia with at least 20% blasts in the bone marrow or blood, and either a previous history of myelodysplastic syndrome, multilineage dysplasia or myelodysplastic syndrome-related cytogenetic abnormalities. There is no history of prior cytotoxic therapy for an unrelated disorder, and there is absence of the molecular abnormalities that are present in acute myeloid leukemia with recurrent genetic abnormalities.

**Synonyms:** - AML with Myelodysplasia-Related Changes - AML with Myelodysplasia-Related Changes - AML with Myelodysplasia-related Changes - AML with myelodysplasia-related changes - AML-MRC - Acute Myeloid Leukemia with Myelodysplasia-Related Changes - Acute Myeloid Leukemia with Myelodysplasia-Related Changes - Acute Myeloid Leukemia with Myelodysplasia-Related Changes - Acute Myeloid Leukemia with Myelodysplasia-Related Changes - Acute myeloid leukemia with myelodysplasia-related changes