WH, Rat Strain

**Semantic type:** Mammal

**Definition:** A Wistar substrain established in Hanover, Germany (1964), this rat breed is a white albino with pink eyes, genotype c. The WH rat has a low incidence of overall spontaneous tumor formation; the most common in males being pituitary adenomas while females exhibit spontaneous mammary, thyroid, and pituitary adenomas. This is a multi-purpose research strain and applications include aging, oncology, toxicology, and safety and efficacy testing.

**Synonyms:** - WH - WISTAR HAN - Wistar Han