Sodium Fluoride F-18

**Semantic type:** Indicator, Reagent, or Diagnostic Aid|Pharmacologic Substance

**Definition:** A radiopharmaceutical consisting of the sodium salt of fluorine F 18 fluoride with radioisotopic and bone mineralizing activities. Fluoride binds to calcium ions in hydroxyapatite crystals in bone. The uptake and incorporation of positron-emitting fluorine F 18 fluoride into bone can be imaged using positron emission tomography (PET) or single-photon emission computed tomography (SPECT), allowing visualization of malignant bone lesions in which regional blood flow and bone turnover are increased.

**Synonyms:** - 18 F-NaF - F-18 NaF - Fluorine F 18 Sodium Fluoride - Fluorine F 18 Sodium Fluoride - NaF F18 - SODIUM FLUORIDE F-18 - Sodium Fluoride F18