Aplaviroc Hydrochloride

**Semantic type:** Pharmacologic Substance

**Definition:** A hydrochloride salt form of Aplaviroc, a C-C Chemokine Receptor Type 5 (CCR5) antagonist with activity against HIV-1. Aplaviroc inhibits HIV-1 entry via CCR5 coreceptor interaction.

**Synonyms:** - 4-(4-(((3R)-1-Butyl-3-((R)-cyclohexylhydroxymethyl)-2,5-dioxo-1,4,9- triazaspiro(5.5)undec-9-yl)methyl)phenoxy)benzoic Acid Hydrochloride - APLAVIROC HYDROCHLORIDE - Aplaviroc HCl - GW873140A