Nitrocefin

**Semantic type:** Antibiotic|Pharmacologic Substance

**Definition:** A beta-lactam antibiotic, with diagnostic properties. Nitrocefin is sensitive to hydrolysis by all lactamases produced by gram-positive and gram-negative bacteria. This agent undergoes a color change as its amide bond is hydrolyzed by beta-lactamase, making it useful as a reagent in beta-lactamase activity studies.

**Synonyms:** - 3-(2,4-Dinitrostyryl)-(6R, 7R)-7-(2-thienylacetamido)-ceph-3-em-4-carboxylic Acid - NITROCEFIN