CHFR wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CHFR wild-type allele is located in the vicinity of 12q24.33 and is approximately 47 kb in length. This allele, which encodes E3 ubiquitin-protein ligase CHFR protein, plays a role in the regulation of mitosis. Mutation or silencing of the gene is associated with multiple cancers.

**Synonyms:** - Checkpoint with Forkhead and Ring Finger Domains wt Allele - FLJ10796 - FLJ33629 - RNF116 - RNF196