Clofenamide

**Semantic type:** Pharmacologic Substance

**Definition:** A benzenedisulfonamide-based agent and carbonic anhydrase (CA) inhibitor with diuretic activity. Clofenamide inhibits CA, thereby preventing sodium, bicarbonate and thus water reabsorption in the proximal convoluted tubule resulting in diuresis.

**Synonyms:** - CLOFENAMIDE