Alamifovir

**Semantic type:** Pharmacologic Substance

**Definition:** A purine nucleotide analog prodrug with activity against wild-type and lamivudine-resistant hepatitis B virus (HBV). Alamifovir acts by inhibiting viral DNA priming and viral DNA packaging, thereby decreasing HBV replication.

**Synonyms:** - ALAMIFOVIR - Bis(2,2,2-trifluoroethyl) ((2-{2-amino-6-((4-methoxyphenyl)sulfanyl)-9H-purin-9-yl}ethoxy)methyl)phosphonate - LY 582563 - LY582563 - MCC 478 - MCC-478