HPGD wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human HPGD wild-type allele is located within 4q34-q35 and is approximately 32 kb in length. This allele, which encodes 15-hydroxyprostaglandin dehydrogenase [NAD+] protein, plays a role in the regulation of prostaglandin metabolism. Mutation of the gene is associated with primary hypertrophic osteoathropathy autosomal recessive and cranioosteoarthropathy.

**Synonyms:** - 15-Hydroxyprostaglandin Dehydrogenase, Type I Gene - 15-PGDH - Hydroxyprostaglandin Dehydrogenase 15-(NAD) wt Allele - PGDH - PGDH1 - PHOAR1 - SDR36C1 - Short Chain Dehydrogenase/Reductase Family 36C, Member 1 Gene