LRRK2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human LRRK2 wild-type allele is located in the vicinity of 12q12 and is approximately 144 kb in length. This allele, which encodes leucine-rich repeat serine/threonine-protein kinase 2 protein, may be involved in the mediation of protein phosphorylation. Mutation in the gene are associated with Parkinson disease 8.

**Synonyms:** - AURA17 - DARDARIN - Leucine-Rich Repeat Kinase 2 wt Allele - PARK8 - Parkinson Disease (Autosomal Dominant) 8 Gene - RIPK7 - ROCO2