Fentanyl Buccal Soluble Film

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** A transmucosal formulation consisting of a small, mucoadhesive, bioerodible polymer disc formulated with the citrate salt of fentanyl, a synthetic anilidopiperidine opioid with analgesic activity. Upon application, fentanyl buccal soluble film rapidly releases fentanyl which is quickly absorbed into the systemic circulation. Fentanyl selectively binds to and activates mu-opioid receptors in the central nervous system (CNS), thereby mimicking the effects of endogenous opiates.

**Synonyms:** - BEMA Fentanyl - Bioerodible Mucoadhesive Fentanyl - Onsolis