APL Differentiation Syndrome

**Semantic type:** Disease or Syndrome

**Definition:** A syndrome observed in patients with acute promyelocytic leukemia treated with all-trans retinoic acid. It is characterized by weight gain, dyspnea, pleural and pericardial effusions, leukocytosis, and renal failure.

**Synonyms:** - Differentiation Syndrome - Retinoic Acid Syndrome - Retinoic Acid Syndrome - Retinoic acid syndrome