LRIG1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human LRIG1 wild-type allele is located in the vicinity of 3p14 and is approximately 122 kb in length. This allele, which encodes leucine-rich repeats and immunoglobulin-like domains protein 1, plays a role in the modulation of signal transduction. Aberrant expression of the gene may be associated with increased breast cancer risk.

**Synonyms:** - DKFZp586O1624 - LIG-1 - LIG1 - Leucine-Rich Repeat Protein LRIG1 Gene - Leucine-Rich Repeats and Immunoglobulin-Like Domains 1 wt Allele - Ortholog of Mouse Integral Membrane Glycoprotein Lig-1 Gene