Azalanstat

**Semantic type:** Pharmacologic Substance

**Definition:** A synthetic imidazole that inhibits hepatic cholesterol biosynthesis by inhibiting the cytochrome P450 enzyme lanosterol 14alpha-demethylase. In an animal model, Azalanstat lowered serum cholesterol in a dose-depended manner.

**Synonyms:** - 1-(((2S,4S)-4-(((p-Aminophenyl)thio)methyl)-2-(p-chlorophenethyl)-1,3-dioxolan-2-yl)methyl)imidazole - AZALANSTAT - RS-21607