TTR wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human TTR wild-type allele is located in the vicinity of 18q12.1 and is approximately 7 kb in length. This allele, which encodes transthyretin protein, plays a role in the stabilization and transport of thyroxine and retinol. Mutations in the gene are associated with hyperthyroxinemia and amyloidosis types 1 and 7.

**Synonyms:** - ATTR - CTS - CTS1 - Carpal Tunnel Syndrome 1 Gene - Epididymis Luminal Protein 111 Gene - HEL111 - HsT2651 - PALB - Prealbumin, Amyloidosis Type I Gene - Prealbumin, Thyroxine-Binding Gene - TBPA - Transthyretin wt Allele