IKZF3 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human IKZF3 wild-type allele is located in the vicinity of 17q21 and is approximately 99 kb in length. This allele, which encodes zinc finger protein Aiolos, is involved in the modulation of both lymphocyte development and transcription. Genetic variation may be associated with both the occurrence and relapse of acute lymphoblastic leukemia.

**Synonyms:** - AIO - AIOLOS - IKAROS Family Zinc Finger 3 (Aiolos) Gene - IKAROS Family Zinc Finger 3 wt Allele - IMD84 - ZNFN1A3 - Zinc Finger Protein, Subfamily 1A, 3 (Aiolos) Gene - Zinc Finger Protein, Subfamily 1A, Member 3 Gene