LEF1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human LEF1 wild-type allele is located within 4q23-q25 and is approximately 121 kb in length. This allele, which encodes lymphoid enhancer-binding factor 1 protein, is involved in the mediation of both transcription and signal transduction. Genetic variation may be associated with both the occurrence and relapse of acute lymphoblastic leukemia.

**Synonyms:** - DKFZp586H0919 - Lymphoid Enhancer-Binding Factor 1 wt Allele - TCF1ALPHA