BTG1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human BTG1 wild-type allele is located in the vicinity of 12q22 and is approximately 3 kb in length. This allele, which encodes protein BTG1, which plays a role in the modulation of cellular proliferation. Genetic variation may be associated with the relapse of acute lymphoblastic leukemia. The BTG1 gene and the MYC gene are involved in a chromosomal aberration, translocation t(8;12)(q24;q22), which may be associated with B-cell chronic lymphocytic leukemia.

**Synonyms:** - APRO2 - B-Cell Translocation Gene 1, Anti-Proliferative Gene - B-Cell Translocation Protein 1 Gene - BTG Anti-Proliferation Factor 1 wt Allele