SIRT1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human SIRT1 wild-type allele is located in the vicinity of 10q21.3 and is approximately 34 kb in length. This allele, which encodes NAD-dependent protein deacetylase sirtuin-1 protein, may play a role in the attenuation of protein acetylation. Genetic variation may be associated with the relapse of acute lymphoblastic leukemia.

**Synonyms:** - HST2, S. cerevisiae, Homolog of Gene - SIR2 - SIR2, S. cerevisiae, Homolog-Like 1 Gene - SIR2-ALPHA - SIR2L1 - SIR2alpha - Sirtuin (Silent Mating Type Information Regulation 2 Homolog) 1 (S. cerevisiae) Gene - Sirtuin (Silent Mating Type Information Regulation 2, S. cerevisiae, Homolog) 1 Gene - Sirtuin 1 wt Allele