Progressive Hairy Cell Leukemia Initial Treatment

**Semantic type:** Neoplastic Process

**Definition:** A hairy cell leukemia requiring initial treatment because of the presence of signs of progression. Signs of progression include cytopenia (especially if symptomatic), increasing splenomegaly, and infectious complications. Therapy is not necessary if the patients are asymptomatic and the blood counts are maintained in an acceptable range.

**Synonyms:** - Progressive Hairy Cell Leukemia, Initial Treatment