Falnidamol

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** A pyrimido-pyrimidine with antitumor activity. BIBX 1382 inhibits the intracellular tyrosine kinase domain of the Epidermal Growth Factor Receptor (EGFR) thus specifically reversing the aberrant enzymatic activity from overexpressed and constitutively activated EGFR, and subsequently inhibiting cell proliferation and inducing cell differentiation.

**Synonyms:** - BIBX 1382 - BIBX-1382 - BIBX1382 - EGFR Inhibitor BIBX 1382 - FALNIDAMOL