Fenfluramine

**Semantic type:** Pharmacologic Substance

**Definition:** An amphetamine derivative and a sympathomimetic stimulant with appetite-suppressant property. Fenfluramine, which was part of the Fen-Phen anti-obesity medication, stimulates the release of serotonin from vesicular storage, and modulates serotonin transporter function. Since serotonin regulates mood and appetite, among other functions, increased serotonin level results in a feeling of fullness and loss of appetite.

**Synonyms:** - 1-(meta-Trifluoromethyl-phenyl)-2 Ethylaminopropane - 2-Ethylamino-1-(3-trifluoromethylphenyl)propane - 3-(Trifluoromethyl)-N-ethyl-alpha-methylphenethylamine - FENFLURAMINE