Tavaborole

**Semantic type:** Pharmacologic Substance

**Definition:** A boron-containing small molecule antifungal agent with broad-spectrum activity against filamentous fungi, including both mold and yeast. 5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole inhibits fungal cytoplasmic leucyl-tRNA synthetase by preventing catalytic turnover, thus inhibiting synthesis of leucyl-tRNA(Leu) and consequentially blocking protein synthesis.

**Synonyms:** - 5-Fluoro-1,3-Dihydro-1-Hydroxy-2,1-Benzoxaborole - AN2690 - TAVABOROLE