Lifibrol

**Semantic type:** Pharmacologic Substance

**Definition:** A novel lipid-lowering agent with a complicated mechanism of action. Lifibrol may affect bile acid metabolism, enhance sterol excretion, reduce cholesterol absorption, or enhance synthesis or sensitivity of the LDL receptors. In studies, its lipid-lowering effects were of a magnitude similar to that of the statins, but unlike statins, it had the ability to lower Lp(a), a risk factor in atherosclerosis.

**Synonyms:** - K12.148 - LIFIBROL