Acute Myeloid Leukemia (Megakaryoblastic) with t(1;22)(p13.3;q13.1); RBM15-MKL1

**Semantic type:** Neoplastic Process

**Definition:** An acute myeloid leukemia associated with t(1;22)(p13.3;q13.1) resulting in the expression of RBM15-MKL1 fusion protein. It affects infants and children and usually shows megakaryocytic maturation.

**Synonyms:** - AML (Megakaryoblastic) with t(1;22)(p13;q13); RBM15-MKL1 - AML (megakaryoblastic) with t(1;22) (p13;q13); RBM15-MKL1 - AML (megakaryoblastic) with t(1;22)(p13.3;q13.3); RBM15-MKL1 - Acute Myeloid Leukemia (Megakaryoblastic) with t(1;22)(p13.3;q13.1); RBM15- MRTFA - Acute Myeloid Leukemia (Megakaryoblastic) with t(1;22)(p13.3;q13.1); RBM15-MKL1 Fusion - Acute Myeloid Leukemia (Megakaryoblastic) with t(1;22)(p13.3;q13.1); RBM15::MLK1 Fusion - Acute Myeloid Leukemia (Megakaryoblastic) with t(1;22)(p13.3;q13.1); RBM15::MRTFA - Acute Myeloid Leukemia (Megakaryoblastic) with t(1;22)(p13;q13); RBM15-MKL1 - Acute Myeloid Leukemia (Megakaryoblastic) with t(1;22)(p13;q13); RBM15-MKL1 - Acute Myeloid Leukemia with RBM15-MRTFA Fusion - Acute Myeloid Leukemia with RBM15::MRTFA Fusion - Acute myeloid leukemia (megakaryoblastic) with t(1;22)(p13;q13); RBM15-MKL1