Recombinant Somatostatin

**Semantic type:** Chemical Viewed Functionally

**Definition:** A recombinant peptide chemically identical or similar to endogenous somatostatin. Somatostatin is a cyclic tetradecapeptide regulating many endocrine and nervous system functions. Somatostatin inhibits release of adenohypophyseal growth hormone, thyrotropin and corticotropin, pancreatic insulin and glucagon, gastric mucosal gastrin, intestinal mucosal secretin, and renal renin by binding to specific somatostatin receptors (SSTR), which are cell surface G protein-coupled receptors expressed in a tissue-specific manner.

**Synonyms:** - AY 24910 - GH-RIH - Growth Hormone Inhibiting Hormone - Panhibin - SOMATOSTATIN - SRIF - Somatostatin - Somatotropin Release Inhibiting Factor