Pirlimycin

**Semantic type:** Amino Acid, Peptide, or Protein|Antibiotic|Pharmacologic Substance

**Definition:** A derivative of clindamycin with a 6-membered ring replacing clindamycin's 5-membered ring. Compared to clindimycin, pirlimycin has increased activity against gram-positive bacteria, including Staphylococcus aureus and coagulase negative species of Staphylococcus and Streptococcus. This agent is primarily used in the treatment of mastitis in cattle.

**Synonyms:** - Methyl(2S-cis)-7-chloro-6,7,8-trideoxy-6[[(4-ethyl-2-piperidinyl) carbonyl]amino]-1-thio-L-threo-alpha-D-galacto-octopyranoside - PIRLIMYCIN - U-57,930 - U-57930E