Prorenoate Potassium

**Semantic type:** Pharmacologic Substance

**Definition:** The potassium salt form of prorenoate, a steroidal aldosterone antagonist with potassium-sparing diuretic activity. Prorenoate antagonizes the activity of aldosterone at the mineralocorticoid receptor in the nephron and thereby prevents sodium reabsorption. This interferes with the sodium/potassium exchanger and causes sodium and water excretion while reducing potassium excretion.

**Synonyms:** - PRORENOATE POTASSIUM