Myeloid/Lymphoid Neoplasms with PDGFRA Rearrangement

**Semantic type:** Neoplastic Process

**Definition:** Hematologic neoplasms characterized by the rearrangement of the PDGFRA gene, most often resulting in the formation of FIP1L1-PDGFRA fusion transcripts. Patients usually present with chronic eosinophilic leukemia, and less often with acute myeloid leukemia or T-lymphoblastic leukemia.

**Synonyms:** - M/LN-eo with PDGFRA Rearrangement - Myeloid and Lymphoid Neoplasms with PDGFRA Rearrangement - Myeloid and lymphoid neoplasms with PDGFRA rearrangement - Myeloid/Lymphoid Neoplasm with PDGFRA Rearrangement