Myeloid/Lymphoid Neoplasms with PDGFRB Rearrangement

**Semantic type:** Neoplastic Process

**Definition:** Myeloid and rarely lymphoid neoplasms characterized by the rearrangement of the PDGFRB gene, most often resulting in the formation of ETV6-PDGFRB fusion transcripts. Patients usually present with chronic myelomonocytic leukemia and less often with atypical chronic myeloid leukemia, or chronic eosinophilic leukemia.

**Synonyms:** - M/LN-eo with PDGFRB Rearrangement - Myeloid Neoplasms with PDGFRB Rearrangement - Myeloid and Lymphoid Neoplasms with PDGFRB Rearrangement - Myeloid neoplasms with PDGFRB rearrangement - Myeloid/Lymphoid Neoplasm with PDGFRB Rearrangement