KLF1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human KLF1 wild-type allele is located within 19p13.13-p13.12 and is approximately 3 kb in length. This allele, which encodes Krueppel-like factor 1 protein, plays a role in the regulation of both transcription and erythrocyte development. Heterozygous loss-of-function mutations in the gene are associated with the blood group-Lutheran inhibitor phenotype.

**Synonyms:** - EKLF - EKLF/KLF1 - Erythroid Kruppel-Like Factor Gene - HBFQTL6 - INLU - Kruppel Like Factor 1 wt Allele - Kruppel-Like Factor 1 (Erythroid) Gene