Long-Chain Acyl-CoA Dehydrogenase Deficiency

**Semantic type:** Disease or Syndrome

**Definition:** A genetic disorder characterized by deficiency of the enzyme long-chain acyl-coenzyme A dehydrogenase that metabolizes long-chain fatty acids. Signs and symptoms appear in infancy or childhood and may be triggered during fasting, illness or exercise. They include hypoglycemia, muscle weakness and lethargy.

**Synonyms:** - Acyl-CoA Dehydrogenase, Long-Chain Deficiency - LCAD - LCAD - Long-Chain Acyl-Coenzyme A Dehydrogenase Deficiency - Long-Chain Acyl-Coenzyme A Dehydrogenase Deficiency