Medium-Chain Acyl-CoA Dehydrogenase Deficiency

**Semantic type:** Disease or Syndrome

**Definition:** A genetic disorder characterized by deficiency of the enzyme medium-chain acyl-coenzyme A dehydrogenase that metabolizes medium-chain fatty acids. Signs and symptoms appear in infancy or childhood and may be triggered during fasting or illness. They include vomiting, hypoglycemia and lethargy.

**Synonyms:** - Acyl-CoA Dehydrogenase, Medium-Chain Deficiency - MCAD - MCAD - Medium-Chain Acyl-Coenzyme A Dehydrogenase Deficiency - Medium-Chain Acyl-Coenzyme A Dehydrogenase Deficiency