Diffuse Cerebral Sclerosis of Schilder

**Semantic type:** Disease or Syndrome

**Definition:** A rare congenital demyelinating disorder affecting the central nervous system. It is characterized by a demyelinating destructive lesion affecting an entire brain lobe or hemisphere. Signs and symptoms include dementia, cortical deafness and blindness, pseudobulbar palsy, and hemiplegia.

**Synonyms:** - Diffuse sclerosis of central nervous system