PALB2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PALB2 wt allele is located in the vicinity of 16p12.1 and is approximately 38 kb in length. This allele, which encodes partner and localizer of BRCA2 protein, may play roles in the repair of damaged DNA and DNA damage-induced checkpoints. Mutations in this gene are associated with about 3% of pancreatic carcinomas.

**Synonyms:** - DKFZp667I166 - DKFZp686E1054 - FANCN - FLJ21816 - Fanconi Anemia, Complementation Group N Gene - PNCA3 - Partner and Localizer of BRCA2 wt Allele