IDH2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human IDH2 wt allele is located in the vicinity of 15q26.1 and is approximately 18 kb in length. This allele, which encodes isocitrate dehydrogenase 2 (NADP+) mitochondrial protein, plays a role in intermediary metabolism. Mutations in this gene are associated with astrocytoma, oligodendroglioma and secondary glioblastoma.

**Synonyms:** - D2HGA2 - ICD-M - IDH - IDHM - IDP - IDPM - Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial wt Allele - mNADP-IDH