Hereditary Melanoma

**Semantic type:** Neoplastic Process

**Definition:** A melanoma defined by the presence of multiple cases of cutaneous melanoma among blood-relatives on the same side of the family. It is caused by germline mutations in the CDKN2A or CDK4 genes. It is associated with an increased risk of pancreatic cancer in a subset of CDKN2A families (WHO, 2006).

**Synonyms:** - Familial Cutaneous Melanoma - Familial Melanoma - Hereditary Cutaneous (Skin) Melanoma - Hereditary Cutaneous Melanoma - Melanoma, Familial