Spinal and Bulbar Muscular Atrophy, X-linked 1

**Semantic type:** Disease or Syndrome

**Definition:** A rare, slowly progressive degenerative disorder affecting males. It is caused by mutations in the androgen receptor (AR) gene. It is characterized by bulbar and limb muscle weakness and atrophy, and gynecomastia.

**Synonyms:** - Kennedy Disease - SBMA - SMAX1 - Spinal and Bulbar Muscular Atrophy