Talc

**Semantic type:** Biomedical or Dental Material|Inorganic Chemical|Pharmacologic Substance

**Definition:** Finely-powdered native hydrous magnesium silicate. When administered into the pleural space, talc initiates an inflammatory reaction, resulting in adhesion of the visceral pleura to the parietal pleura and fibrosis, thereby effectively closing the pleural space and preventing further accumulation of fluid. This agent exhibits no intrinsic antineoplastic activity. (NCI04)

**Synonyms:** - Sclerosol Intrapleural Aerosol - Sterile Talc Powder - Steritalc - TALC - sterile talc powder - talc