Single Palmar Crease

**Semantic type:** Congenital Abnormality

**Definition:** A single transverse palmar crease is found in 5% of newborns and is frequently inherited as a familial trait. However, single palmar creases can be associated with Down's syndrome and other genetic disorders, or with fetal alcohol syndrome.

**Synonyms:** - Simian Crease - Single Transverse Palmar Crease